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Step 2: Support the foundation

Routine labs may not show local skin or connective-tissue response

Clinical observations further indicate that high-intensity interval training and long-term moderate-intensity aerobic exercise significantly reduce coronary plaque volume and enhance plaque stability

Although the mortality rate and disability-adjusted life years showed a decreasing trend from 1990 to 2021, the incidence and prevalence continue to rise due to population growth and aging, and the ASIR is projected to increase to 0.57 per 100,000 population by 2050 (Huang et al., 2025

Atay S, Correa A, Hofstetter WL, Mehran RJ, Rice DC, Roth JA, Sepesi B, Swisher SG , Vaporciyan AA, Walsh G, Antonoff MB

The European Food Safety Authority (EFSA) permits up to 0.9 mg/day of DAO for special medical purposes, with current studies investigating the efficacy of plant-based DAO sources